Again autographed and bowed out (8)
I believe the answer is:
resigned
'bowed out' is the definition.
'resigned' can be an answer for 'out' (thesaurus). I'm unsure of the 'bowed' bit.
'again autographed' is the wordplay.
'again' becomes 're' (prefix meaning 'again').
'autographed' becomes 'signed' (similar in meaning).
're'+'signed'='RESIGNED'
'and' is the link.
Can you help me to learn more?
(Other definitions for resigned that I've seen before include "Defeatist" , "Stopped working" , "philosophical" , "Packed it in!" , "Quit" .)