An Italian could start something stimulating (5)
I believe the answer is:
tonic
'stimulating' is the definition.
(thesaurus)
I cannot understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for tonic that I've seen before include "Invigorating medicine - keynote" , "Producing tension of muscles" , "Carbonated mixer" , "Keynote of a scale" , "requirement for invigoration?" .)