Animal with arms raised (4)
I believe the answer is:
stag
'animal' is the definition.
(stag is a kind of animal)
'arms raised' is the wordplay.
'arms' becomes 'gats' (gat is a kind of arm).
'raised' shows that the letters should be reversed in order (going up in a down clue).
'gats' reversed gives 'STAG'.
'with' acts as a link.
(Other definitions for stag that I've seen before include "Excluding women" , "Antlered animal" , "speculator wanting quick profit" , "Stockmarket operator gambling on a quick profit" , "Male-only" .)