Crossword Genius

Annoy persistently

Ross

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6

6*

(Other definitions for plague that I've seen before include "Contagious disease with a high death rate" , "Epidemic disease with a high death rate" , "Destructive, highly contagious disease" , "Pester with deadly disease" , "Epidemic diseases with high mortality" .)

I've seen this clue in The Washington Post and The Irish Times.
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