Anxiety's extreme, going over point (4)
I believe the answer is:
fear
'anxiety's' is the definition.
(fear is a kind of anxiety)
'extreme going over point' is the wordplay.
'extreme' becomes 'far' (I've seen this in other clues).
'going over' is an insertion indicator.
'point' becomes 'e' (E is an example).
'far' placed around 'e' is 'FEAR'.
(Other definitions for fear that I've seen before include "awe" , "Cutting edge" , "Fright" , "Respect" , "Qualms" .)