Aphorisms embodied in a large manuscript (6)
I believe the answer is:
maxims
'aphorisms embodied' is the definition.
I can't judge whether this defines the answer.
'large manuscript' is the wordplay.
'large' becomes 'maxi' (I can't explain this - if you can you should give a lot more credence to this answer).
'manuscript' becomes 'ms' (abbreviation for manuscript).
'maxi'+'ms'='MAXIMS'
'in a' is the link.
Can you help me to learn more?
(Other definitions for maxims that I've seen before include "Axioms, precepts" , "General truths or rules of conduct" , "gnomes" .)