Are men out to help her? (6)
I believe the answer is:
maiden
'are men' is the definition.
The answer and definition are not the same part of speech. However, past participle verbs and adjectives can sometimes mean the same thing.
'out to help her?' is the wordplay.
'out' is an insertion indicator.
'to help' becomes 'main' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'her?' becomes 'De'.
'main' placed around 'de' is 'MAIDEN'.
Can you help me to learn more?
(Other definitions for maiden that I've seen before include "No-score over" , "First (speech)" , "Damsel" , "Six dot balls" , "clothes horse" .)