As is, crane's insecure (7)
I believe the answer is:
arsenic
'as' is the definition.
(As is the chemical symbol for arsenic)
'is crane's insecure' is the wordplay.
'is crane' anagrams to 'ARSENIC'.
Though, I am not clear how this is indicated.
Can you help me to learn more?
(Other definitions for arsenic that I've seen before include "As briefly identified" , "Toxic metallic element used as rat poison" , "killer" , "Poison used in pesticides and weedkillers" , "Element with many poisonous compounds" .)