Assiduously, tho’ harshly (10)
I believe the answer is:
thoroughly
'assiduously' is the definition.
(thesaurus)
'tho' harshly' is the wordplay.
'harshly' becomes 'roughly' (I can't explain this - if you can you should believe this answer much more).
'tho'+'roughly'='THOROUGHLY'
Can you help me to learn more?
(Other definitions for thoroughly that I've seen before include "Musical with Julie Andrews" , "Completely" , "More than a bit" , "Quite" , "Really" .)