At present, no way! (3)
I believe the answer is:
now
'at present' is the definition.
(synonyms)
'no way' is the wordplay.
'way' becomes 'w' (Compass direction - West).
'no'+'w'='NOW'
(Other definitions for now that I've seen before include "At the present time" , "At present, this instant" , "Today" , "Immediately" , "At this moment in time" .)