Awful bore in Lausanne is quite contrary (12)
I believe the answer is:
unreasonable
'awful' is the definition.
Both the answer and definition are adjectives. Perhaps there's an association between them I don't understand?
I don't understand how the rest of the clue works.
Can you help me to learn more?
(Other definitions for unreasonable that I've seen before include "Immoderate" , "Not fair" , "dear?" , "Beyond acceptable limits" , "Unacceptable" .)