Bacon, for one, made extremely vacuous art (4)
I believe the answer is:
meat
'bacon for one' is the definition.
(bacon is a kind of meat)
'made extremely vacuous art' is the wordplay.
'extremely' means to remove the middle letters.
'vacuous' says to hollow out the word (remove centre letters).
'made' with its middle taken out is 'me'.
'art' with its middle taken out is 'at'.
'me'+'at'='MEAT'
(Other definitions for meat that I've seen before include "Eg, beef or pork" , "Food for carnivores" , "Beef, chicken, pork etc" , "Ham, pork, chicken etc" , "17 [ESSENCE]" .)