Be more active when uneasy (8)
I believe the answer is:
restless
'uneasy' is the definition.
(I know that uneasy can be written as restless)
'be more active' is the wordplay.
'be' becomes 'rest' (resting is a kind of being).
'more active' becomes 'less' (I can't explain this - if you can you should believe this answer much more).
'rest'+'less'='RESTLESS'
'when' acts as a link.
Can you help me to learn more?
(Other definitions for restless that I've seen before include "Fidgety - unable to sleep" , "Wakeful" , "Never still" , "Uneasy and agitated" , "Ceaselessly in motion" .)