Become more distant — and give up again? (6)
I believe the answer is:
recede
I believe this is a double definition.
'become more distant' is the first definition.
(I've seen this before)
'give up again?' is the second definition.
('cede' can be a synonym for 'give up' so perhaps 'recede' is OK for 'give up again')
'and' is the link.
(Other definitions for recede that I've seen before include "Go backwards" , "Start balding" , "Withdraw" , "Become more distant" , "Go back, ebb" .)