Big fan that's in use irregularly (10)
I believe the answer is:
enthusiast
'big fan' is the definition.
'enthusiast' can be an answer for 'fan' (I've seen this before). I'm unsure of the 'big' bit.
'that's in use irregularly' is the wordplay.
'irregularly' is an anagram indicator.
'thats'+'in'+'use'='thatsinuse'
'thatsinuse' is an anagram of 'ENTHUSIAST'.
Can you help me to learn more?
(Other definitions for enthusiast that I've seen before include "Ardent supporter" , "one not at all cool" , "Devotee" , "buff" , "One deeply interested in a subject" .)