Crossword Genius

Blithe man's set to ruin business (13)

Ross

I believe the answer is:

establishment

'business' is the definition.
(I've seen this before)

'blithe man's set to ruin' is the wordplay.
'to ruin' indicates anagramming the letters.
'blithe'+'mans'+'set'='blithemansset'
'blithemansset' is an anagram of 'ESTABLISHMENT'.

(Other definitions for establishment that I've seen before include "Those in power" , "Action of setting up on a permanent basis" , "Institutionalized authority" , "system" , "being incorporated in this" .)

I've seen this clue in The Telegraph.
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