Blood? Good Lord (4)
I believe the answer is:
king
'lord' is the definition.
'blood? good' is the wordplay.
'blood?' becomes 'kin' (blood is a kind of kin).
'good' becomes 'g' (abbreviation).
'kin'+'g'='KING'
(Other definitions for king that I've seen before include "Card, draughts piece" , "US civil rights leader, assassinated 1968" , "as Solomon was" , "Honour for man" , "Recipient of 10 21 [VELODROME GOLD]" .)