Blood vessel - vital and prone to get damaged (6,4)
I believe the answer is:
portal vein
'blood vessel' is the definition.
(portal vein is a kind of blood vessel)
'vital and prone to get damaged' is the wordplay.
'and' means one lot of letters go next to another.
'to get damaged' indicates an anagram.
'vital'+'prone'='vitalprone'
'vitalprone' with letters rearranged gives 'PORTAL VEIN'.
(Another definition for portal vein that I've seen is " What supplies liver".)
I've seen this clue in The Independent.
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