Boys losing heart for women of refinement (6)
I believe the answer is:
ladies
'women of refinement' is the definition.
(I've seen this before)
'boys losing heart' is the wordplay.
'boys' becomes 'laddies' (laddie is a kind of boy).
'losing heart' means to remove the middle letters.
'laddies' with its middle taken out is 'LADIES'.
'for' acts as a link.
(Other definitions for ladies that I've seen before include "9th" , "Public facility" , "...... and gentlemen" , "Convenience" , "Females" .)