Brass bottle (5)
I believe the answer is:
nerve
This clue is a double definition.
'brass' is the first definition.
('nerve' can be a synonym of 'brass')
'bottle' is the second definition.
(thesaurus)
(Other definitions for nerve that I've seen before include "Hold it and maintain courage" , "Fibre that carries instructions to the brain" , "Steadiness, courage" , "Audacity (informal)" , "Strand of body tissue" .)