Brief absences from school (4)
I believe the answer is:
hols
'brief absences' is the definition.
The definition suggests a plural noun which matches the answer.
'from school' is the wordplay.
'from' becomes 'hol' (I can't explain this - if you can you should give a lot more credence to this answer).
'school' becomes 'S'.
'hol'+'s'='HOLS'
Can you help me to learn more?
(Other definitions for hols that I've seen before include "vacation" , "Time off school" , "Leave" .)