Call into question male with boxer entering home (6)
I believe the answer is:
impugn
'call into question' is the definition.
(I've seen this before)
'male with boxer entering home' is the wordplay.
'male' becomes 'm' (common abbreviation).
'with' says to put letters next to each other.
'boxer' becomes 'pug' (I've seen this before).
'entering' is an insertion indicator.
'home' becomes 'in' ('he's home' can mean 'he's in').
'm'+'pug'='mpug'
'mpug' placed into 'in' is 'IMPUGN'.
(Other definitions for impugn that I've seen before include "Express doubts about truth or honesty of, say motives" , "Call into question or attack by words" , "Challenge (e.g. honesty)" , "Call into question; criticise" , "Try to discredit, express doubts about honesty" .)