Charming about injury (4)
I believe the answer is:
harm
'injury' is the definition.
(synonyms)
'charming about' is the wordplay.
'about' indicates the answer is hidden within the clue (the clue goes around or about the answer).
'HARM' can be found hidden inside 'charming'.
(Other definitions for harm that I've seen before include "Hurt, injure" , "Damage, hurt" , "Injure, injury" , "Wound" , "Detriment" .)