Cheated many an individual (4)
I believe the answer is:
done
'cheated' is the definition.
'many an individual' is the wordplay.
I cannot quite understand how this works, but
'many' could be 'd' (Roman numeral for 500) and 'd' is found in the answer.
'an' could be 'one' and 'one' is located in the answer.
No letters remain.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for done that I've seen before include "Managed" , "Cooked; carried out" , "Completed" , "Concluded (and dusted?)" , "Finished or ended" .)