Chemical made from trees (5)
I believe the answer is:
ester
'chemical' is the definition.
(I know that ester is a type of organic compound)
'from trees' is the wordplay.
'from' indicates an anagram (the anagram comes from the same letters).
'trees' is an anagram of 'ESTER'.
'made' acts as a link.
(Other definitions for ester that I've seen before include "Compound formed from acid and alcohol" , "Reset (anag.)" , "Organic compound, rhymes with court joker" , "Organic chemical compound" , "Fat" .)