Children that may be well read? (5)
I believe the answer is:
issue
'children' is the definition.
(issue can mean someone's offspring)
I don't understand the rest of the clue.
Can you help me to learn more?
(Other definitions for issue that I've seen before include "Contentious subject" , "Offspring; publish" , "Offspring; problem" , "Topic; give out" , "that may be taken where there's disagreement?" .)