City in America, ironically! (5)

I believe the answer is:

cairo

'city' is the definition.
(Cairo is an example)

'in america ironically' is the wordplay.
'in' indicates the answer is hidden within the clue.
'CAIRO' can be found hidden inside 'america ironically'.

(Other definitions for cairo that I've seen before include "City near the Nile delta" , "Egyptian capital" , "Egypt's capital" , "Capital of Egypt" , "Al Qahira" .)

I've seen this clue in the Evening Standard.

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