City of northwest Syria (6)

I believe the answer is:

aleppo

(Other definitions for aleppo that I've seen before include "City in Syria - lop ape (anag)" , "Foreign city" , "Lap Poe around the Syrian city" , "Middle East city" , "Largest city in Syria before the massive damage of the civil war" .)

I've seen this clue in The Guardian.

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