City shelter on drugs, outwardly (5)
I believe the answer is:
leeds
'city' is the definition.
(Leeds is an example)
'shelter on drugs outwardly' is the wordplay.
'shelter' becomes 'lee' (I've seen this before).
'on' is a charade indicator (letters next to each other).
'outwardly' means to remove the middle letters (only the outermost letters are used).
'drugs' with its middle taken out is 'ds'.
'lee'+'ds'='LEEDS'
(Other definitions for leeds that I've seen before include "Soccer team" , "City on River Aire" , "22 [FA CUP] runners-up" , "British city and premier division football club" , "Northern town" .)