Claw of one man in a hundred (5)
I believe the answer is:
talon
'claw' is the definition.
(I know that talon is a type of claw)
'one man in a hundred' is the wordplay.
'one man' becomes 'al' (man's name).
'in' indicates putting letters inside.
'a hundred' becomes 'ton' (I've seen this before).
'al' put within 'ton' is 'TALON'.
'of' acts as a link.
(Other definitions for talon that I've seen before include "Claw; undealt cards" , "Bird's claw" , "The stock" , "Tonal (anag.)" , "Prey-bird's claw" .)