Climbs up a sign (6)
I believe the answer is:
scales
I believe this is a double definition.
'climbs up' is the first definition.
(scaling is a kind of climbing up)
'a sign' is the second definition.
(I know that scales is a sign)
(Other definitions for scales that I've seen before include "a number of small plates" , "Balance - climbs" , "Measuring instrument for weighing" , "Instruments for weighing things" , "Sign of the Zodiac - actor" .)