Cocaine’s picked up to tempt (4)
I believe the answer is:
coax
'tempt' is the definition.
(thesaurus)
'cocaine's picked up' is the wordplay.
'cocaine's' becomes 'cokes' ('coke' can be a synonym of 'cocaine').
'picked up' shows a homophone (sound like).
'cokes' sounds like 'COAX'.
'to' is the link.
(Other definitions for coax that I've seen before include "Flatter" , "Get round" , "Inveigle" , "Attempt to manipulate" , "Wheedle, cajole" .)