Colour of most interest (4)
I believe the answer is:
tint
'colour' is the definition.
(I know that tint is a type of colour)
'of most interest' is the wordplay.
'of' says the answer is hidden in the clue.
'TINT' can be found hidden inside 'most interest'.
(Other definitions for tint that I've seen before include "Hue, shade" , "A slighth shade of colour" , "A slight shade of colour" , "'Shade, tone (4)'" , "(Softer variety of) colour" .)