Commercial centre of Newry, for example? (8)
I believe the answer is:
downtown
'commercial centre' is the definition.
'of newry for example?' is the wordplay.
I cannot quite understand how this works, but
'of' could be 'o' and 'o' is found within the answer.
'for' could be 'to' (eg both can mean 'in the opinion of') and 'to' is found within the answer.
This may be the basis of the clue (or it may be nonsense).
(Other definitions for downtown that I've seen before include "Central district in Newcastle" , "Central commercial district (US)" , "Shopping centre" , "US city centre" , "Central Park?" .)