Complain about Menace initially in Beano comic (6)
I believe the answer is:
bemoan
'complain' is the definition.
(bemoaning is a kind of complaining)
'menace initially in beano comic' is the wordplay.
'initially' indicates taking the first letters.
'in' is an insertion indicator.
'comic' indicates anagramming the letters.
The initial letter of 'menace' is 'm'.
'beano' is an anagram of 'beoan'.
'm' going inside 'beoan' is 'BEMOAN'.
'about' is the link.
(Other definitions for bemoan that I've seen before include "Regret, lament" , "Lament, grieve" , "Deplore, lament" , "Complain about, lament" .)