Cosmic comeuppance (5)
I believe the answer is:
karma
'cosmic comeuppance' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for karma that I've seen before include "Buddhist fate; destiny" , "Retribution" , "Moral quality determining future life (Hinduism)" , "In Buddhism, the sum of a person's existence - determines future" , "In Indian philosophy, moral actions are carried by the soul into later lives" .)