Crackpot relation from the east (8)
I believe the answer is:
oriental
'from the east' is the definition.
(I've seen this in another clue)
'crackpot relation' is the wordplay.
'crackpot' indicates an anagram (an eccentric ordering of the letters).
'relation' anagrammed gives 'ORIENTAL'.
(Other definitions for oriental that I've seen before include "from E?" , "Easterner" , "Eastern sort of relation" , "Asiatic, say" , "Korean, for example" .)