Creature with flipping bite (4)
I believe the answer is:
gnat
'creature' is the definition.
(gnat is a kind of creature)
'flipping bite' is the wordplay.
'flipping' is a reversal indicator.
'bite' becomes 'tang' (both can mean a flavour or taste).
'tang' reversed gives 'GNAT'.
'with' is the link.
(Other definitions for gnat that I've seen before include "a little bit of a nuisance" , "Tiny thing" , "Small (swarming) fly" , "insect's" , "Small biting fly" .)