Curse in middle of rubbish day (6)
I believe the answer is:
blight
'curse' is the definition.
(thesaurus)
'middle of rubbish day' is the wordplay.
'middle of' means to look at the middle letters.
'day' becomes 'light' (I've seen this in other clues).
The central letter of 'rubbish' is 'b'.
'b'+'light'='BLIGHT'
'in' acts as a link.
(Other definitions for blight that I've seen before include "Potato disease" , "Problem of plants or urban development" , "Pestilence - state of decay" , "Withering disease (in plants)" , "Setback" .)