Curse MP - he's able to change... (9)
I believe the answer is:
'curse' is the definition.
('blaspheme' can be a synonym of 'curse')
'mp he's able to change' is the wordplay.
'to change' indicates an anagram.
'mphesable' is an anagram of 'BLASPHEME'.
(Other definitions for blaspheme that I've seen before include "Curse profanely" , "Talk irreverently about God and sacred things" , "Say irreverent things about God" , "Speak profanely" , "Curse, profane" .)