Cut loose from a daughter over split (6)
I believe the answer is:
adrift
'cut loose' is the definition.
(I've seen this before)
'a daughter over split' is the wordplay.
'daughter' becomes 'd' (genealogical abbreviation).
'over' says to put letters next to each other (in a down clue, some letters go over others).
'split' becomes 'rift' (I've seen this in other clues).
'a'+'d'+'rift'='ADRIFT'
'from' acts as a link.
(Other definitions for adrift that I've seen before include "Purposeless" , "Going out of control" , "Wandering aimlessly" , "not settled" , "Floating unattached as at sea" .)