Defective region in Evesham is spotted (5)
I believe the answer is:
amiss
'defective' is the definition.
(I've seen this in another clue)
'region in evesham is spotted' is the wordplay.
'region in' indicates a hidden word.
'AMISS' is hidden within 'evesham is spotted'.
(Other definitions for amiss that I've seen before include "Wrongly" , "error" , "Badly - wrong" , "Haywire" , "Wrorg" .)