Department head is driven to protest (7)
I believe the answer is:
dissent
'to protest' is the definition.
(synonyms)
'department head is driven' is the wordplay.
'head' says to take the initial letters.
'driven' becomes 'sent' (I can't explain this - if you can you should believe this answer much more).
The first letter of 'department' is 'd'.
'd'+'is'+'sent'='DISSENT'
Can you help me to learn more?
(Other definitions for dissent that I've seen before include "Raise objections" , "Differ" , "Disagree" , "Dispute" , "Not agree" .)