Depressed daughter thrown out (8)
I believe the answer is:
dejected
'depressed' is the definition.
(similar in meaning)
'daughter thrown out' is the wordplay.
'daughter' becomes 'd' (genealogical abbreviation).
'thrown out' becomes 'ejected' ('eject' can be a synonym of 'throw out').
'd'+'ejected'='DEJECTED'
(Other definitions for dejected that I've seen before include "Depressed and cast down" , "Melancholy" , "Downhearted" , "Despondent" , "Glum" .)