Desire features in witchcraft (4)
I believe the answer is:
itch
'desire' is the definition.
(I know that itch is a more specific form of the action desire)
'features in witchcraft' is the wordplay.
'features in' indicates a hidden word (I've seen 'featured in' mean this).
'ITCH' is hidden in the letters of 'witchcraft'.
(Other definitions for itch that I've seen before include "Prickle" , "Craving" , "Irritating sensation on skin" , "Hunger, longing" , "Prickling" .)