Such a vocal piece creates mayhem (5)
I believe the answer is:
havoc
'mayhem' is the definition.
(I know that mayhem can be written as havoc)
'such a vocal piece' is the wordplay.
'piece' indicates the answer is hidden within the clue.
'HAVOC' is hidden in the letters of 'such a vocal'.
'creates' is the link.
(Other definitions for havoc that I've seen before include "Great confusion" , "Violent and needless disturbance" , "Widespread destruction and great disorder" , "Widepsread destruction" , "Chaos and destruction" .)