Diminutive East Ender feeling restless or uneasy (6)

I believe the answer is:

titchy

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'uneasy' is the definition.
I know nothing about this answer so I cannot judge whether it can be defined by this definition.

'diminutive east ender feeling restless' is the wordplay.
'diminutive east ender feeling' becomes 't' (I am not sure about this - if you are sure you should believe this answer much more).
'restless' becomes 'itchy' (synonyms).
't'+'itchy'='TITCHY'

'or' is the link.

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(Other definitions for titchy that I've seen before include "Very small" , "Tiny" , "Very short" , "Little" .)

I've seen this clue in the Evening Standard.

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