Direction taken into Lowestoft (4)
I believe the answer is:
west
'direction' is the definition.
(compass direction)
'into lowestoft' is the wordplay.
'into' indicates the answer is hidden within the clue.
'WEST' is hidden within 'lowestoft'.
'taken' is the link.
(Other definitions for west that I've seen before include "Colombian with brews (anag)" , "Occident" , "English county" , "The cardinal compass point of 270 degrees" , "One Direction" .)