Disturbance of cast iron sample (4)
I believe the answer is:
stir
'disturbance' is the definition.
('stir' can be a synonym of 'disturbance')
'of cast iron sample' is the wordplay.
'of' indicates the answer is hidden within the clue.
'STIR' is hidden in the letters of 'cast iron sample'.
(Other definitions for stir that I've seen before include "Rouse; prison (colloq.)" , "where porridge is served" , "Detention centre" , "Cause to move in slangy prison" , "Whisk or rotate" .)