Do big trees make up this place? In a sense; largely not! (4,6)
I believe the answer is:
gobi desert
'up this place? in a sense largely not' is the definition.
The definition and answer can be both locations as well as being singular nouns.
Perhaps there's an association between them I don't understand?
'do big trees make' is the wordplay.
'make' indicates an anagram.
'do'+'big'+'trees'='dobigtrees'
'dobigtrees' is an anagram of 'GOBI DESERT'.
Can you help me to learn more?
(Other definitions for gobi desert that I've seen before include "desolate landscape" , "Region of Central Asia" , "Mongolian wasteland" , "Asian wilderness" , "dry expanse" .)